Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 3/20 | 0.70 |
| ▸ | GNB1 | P62873 | 3/20 | 0.70 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588006 | 1.00 | GNG2 (0.70) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL10967109 | 0.87 | GNG2 (0.53) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL14960105 | 0.87 | GNG2 (0.53) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL21436303 | 0.85 | GNG2 (0.51) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL2777300 | 0.82 | GNG2 (1.00) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL13622415 | 0.80 | GNG2 (0.46) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL30355394 | 0.80 | GNG2 (0.46) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL6125804 | 0.80 | GNG2 (0.70) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL14001247 | 0.80 | GNG2 (0.70) | GNG2GNB1PTPN7HTTMEN1 | |
| SCHEMBL1645805 | 0.80 | GNG2 (0.70) | GNG2GNB1PTPN7HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-9248086-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150174026-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2015-06-25 | — | — | US | disclosed |
| US-8932370-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140326269-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2014-11-06 | — | — | US | disclosed |
| US-8758451-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20140013520-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | GNG2 2263/4885GNB1 2876/4885PTPN7 1480/4885 |
| US-20140013520-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | GNG2 2263/4885GNB1 2876/4885PTPN7 1480/4885 |
| US-20150174026-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | GNG2 2263/4885GNB1 2876/4885PTPN7 1480/4885 |
| US-20140326269-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | GNG2 2263/4885GNB1 2876/4885PTPN7 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.