SCHEMBL15424265

SCHEMBL15424265

N#Cc1ccc(-c2cc3c4c(ccc5cc(Br)cc(c54)C3(c3ccccc3)c3ccccc3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.38
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
PDK2 Q15119 1/20 0.36
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ALDH1A3 P47895 1/20 0.34
PGR P06401 2/20 0.34
HDAC8 Q9BY41 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
HRH3 Q9Y5N1 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15907508 0.82 PGR (0.39) PDK2ESR1ESR2PGRHRH3
SCHEMBL12387571 0.81 CYP2A6 (0.39) LMNA
SCHEMBL15424266 0.78 LIPG (0.45) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL31278121 0.78 PDK2 (0.49) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL22345914 0.78 PDK2 (0.49) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL15424277 0.74 ALDH1A1 (0.51) ALDH1A3KDM4ELMNASMN1; SMN2
SCHEMBL12927703 0.74 NPSR1 (0.37) MAOATSHRLMNA
SCHEMBL15316881 0.71 ALDH1A1 (0.35) ESR1ESR2MAOBCYP11B1CYP11B2
SCHEMBL17297060 0.70 PDK2 (0.59) MYCGABRA1GABRG2GABRB3GABRA5
SCHEMBL15424283 0.70 ABCG2 (0.44) MYCGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559310-B2 Compound with electron injection and/or electron transport capabilities and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-31 US disclosed
US-20140014925-A1 NOVEL COMPOUND WITH ELECTRON INJECTION AND/OR ELECTRON TRANSPORT CAPABILITIES AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-01-16 US disclosed