Sugi Predict

Sugi Predict / Compounds / SCHEMBL15426271

SCHEMBL15426271

SCHEMBL15426271

Cc1cnc2c(c1)nc(-c1ccccc1S(=O)(=O)C(C)(C)C)n2C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.38
▸ PDE10A Q9Y233 3/20 0.38
▸ ALOX5AP P20292 1/20 0.37
▸ FEN1 P39748 1/20 0.37
▸ NPC1 O15118 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ KMT2A Q03164 3/20 0.36
▸ AKT1 P31749 2/20 0.36
▸ AKT2 P31751 2/20 0.36
▸ RIPK2 O43353 1/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ HSD11B1 P28845 1/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ PDE2A O00408 1/20 0.33
▸ GRM2 Q14416 1/20 0.33
▸ MEN1 O00255 2/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15426276 0.92 BRD4 (0.38) BRD4PDE10AALOX5APFEN1KMT2A
SCHEMBL15426257 0.88 HSD11B1 (0.47) BRD4PDE10AALOX5APFEN1KMT2A
SCHEMBL15412928 0.86 PDE2A (0.43) PDE10AALOX5APFEN1KMT2ARIPK2
SCHEMBL15412773 0.85 BRD4 (0.40) BRD4PDE10AALOX5APFEN1KMT2A
SCHEMBL15426268 0.84 ALOX5AP (0.39) BRD4PDE10AALOX5APFEN1KMT2A
SCHEMBL15426263 0.82 ALOX5AP (0.40) BRD4PDE10AALOX5APFEN1KMT2A
SCHEMBL15412795 0.81 PDE2A (0.43) PDE10AKMT2AKDM4EALDH1A1PDE2A
SCHEMBL15426266 0.81 BRD4 (0.40) BRD4PDE10AKMT2AAKT1AKT2
SCHEMBL10280992 0.77 USP1 (0.40) BRD4ALOX5APFEN1NPC1RAB9A
SCHEMBL15426465 0.77 HSD11B1 (0.41) BRD4PDE10ANPC1AKT1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 — — US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 — — US disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 — — US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 BRD4 1677/4885PDE10A 3812/4885ALOX5AP 2508/4885
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 BRD4 1616/4885PDE10A 3725/4885ALOX5AP 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.