SCHEMBL15426413

SCHEMBL15426413

CCS(=O)(=O)c1cc(C(F)(F)F)ccc1-c1nc2cc(C)cnc2n1C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 10/20 0.41
POLB P06746 1/20 0.39
S1PR1 P21453 2/20 0.38
SLC40A1 Q9NP59 1/20 0.38
ALOX5AP P20292 3/20 0.37
FEN1 P39748 3/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.36
PDE2A O00408 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10280701 0.93 POLB (0.46) DDR1POLBS1PR1ALOX5APFEN1
SCHEMBL10280794 0.90 LMNA (0.38) DDR1POLBS1PR1SLC40A1ALOX5AP
SCHEMBL15426443 0.89 PDE2A (0.38) DDR1POLBALOX5APFEN1PTGDR2
SCHEMBL15426442 0.88 POLB (0.39) DDR1POLBS1PR1ALOX5APFEN1
SCHEMBL10280999 0.87 POLB (0.38) DDR1POLBS1PR1ALOX5APFEN1
SCHEMBL15426384 0.86 RORC (0.37) DDR1
SCHEMBL15412723 0.85 DDR1 (0.35) DDR1POLBS1PR1ALOX5APFEN1
SCHEMBL16746510 0.85 DDR1 (0.39) DDR1POLBALOX5APPDE2A
SCHEMBL10280987 0.84 POLB (0.45) DDR1POLBALOX5APFEN1PDE2A
SCHEMBL15868290 0.84 POLB (0.44) DDR1POLBS1PR1SLC40A1ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 US disclosed
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-28 US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 US disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 DDR1 3079/4885POLB 4715/4885S1PR1 3006/4885
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SFXN1, OSR1, PIR DDR1 2720/4885POLB 4471/4885S1PR1 734/4885
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 DDR1 3074/4885POLB 4737/4885S1PR1 3091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.