Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.37 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280632 | 0.90 | LIPC (0.40) | LIPCLIPGMMP13MMP2MMP3 | |
| SCHEMBL14830588 | 0.89 | MMP13 (0.40) | LIPCLIPGMMP13MMP2MMP3 | |
| SCHEMBL9108211 | 0.86 | MMP13 (0.45) | MMP13LIPEEPHX2 | |
| SCHEMBL9108220 | 0.86 | MMP13 (0.45) | MMP13LIPEEPHX2 | |
| SCHEMBL9110045 | 0.77 | DPP4 (0.45) | MMP13EPHX2 | |
| SCHEMBL9110055 | 0.77 | DPP4 (0.45) | MMP13EPHX2 | |
| SCHEMBL15428476 | 0.76 | SLC6A4 (0.41) | LIPESLC6A4SLC6A5HRH3HPGD | |
| SCHEMBL14837995 | 0.76 | MMP13 (0.43) | MMP13LIPEEPHX2 | |
| SCHEMBL1689415 | 0.76 | MMP13 (0.43) | MMP13LIPEEPHX2 | |
| SCHEMBL9107353 | 0.76 | MMP13 (0.45) | MMP13EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012075239-A1 | SEROTONIN REUPTAKE INHIBITORS | THERAVANCE, INC. (US) | 2012-06-07 | — | — | WO | disclosed |