Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15433747 | 0.85 | CYP19A1 (0.36) | — | |
| SCHEMBL10015187 | 0.83 | PTGS2 (0.32) | — | |
| SCHEMBL15428934 | 0.78 | NTRK1 (0.39) | — | |
| SCHEMBL15428932 | 0.69 | ADORA2A (0.36) | — | |
| SCHEMBL9890977 | 0.68 | TYR (0.39) | — | |
| SCHEMBL10015185 | 0.67 | BRD4 (0.36) | — | |
| SCHEMBL18900876 | 0.67 | PLAU (0.40) | — | |
| SCHEMBL15433735 | 0.65 | BRD4 (0.43) | — | |
| SCHEMBL9890972 | 0.64 | HTR6 (0.35) | — | |
| SCHEMBL10015189 | 0.63 | BRD4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633320-B2 | Process for preparing bromo-substituted quinolines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-21 | — | — | US | disclosed |