Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428935 | 0.85 | JAK2 (0.31) | — | |
| SCHEMBL18900876 | 0.82 | PLAU (0.40) | CYP19A1CYP11B1CYP11B2SMN1; SMN2NPC1 | |
| SCHEMBL15433735 | 0.80 | BRD4 (0.43) | ALPL | |
| SCHEMBL15433731 | 0.71 | BRD4 (0.42) | CYP19A1CYP11B1CYP11B2SMN1; SMN2NPC1 | |
| SCHEMBL288425 | 0.71 | SYK (0.35) | CYP19A1CYP11B1CYP11B2SMN1; SMN2LMNA | |
| SCHEMBL10046380 | 0.68 | NPC1 (0.34) | NPC1RAB9ALRRK2 | |
| SCHEMBL13074830 | 0.67 | HTR6 (0.39) | CYP19A1CYP11B1CYP11B2SMN1; SMN2KMT2A | |
| SCHEMBL7900338 | 0.66 | HTR6 (0.38) | CYP19A1CYP11B1CYP11B2SMN1; SMN2KMT2A | |
| SCHEMBL7909715 | 0.65 | HTR6 (0.39) | CYP19A1CYP11B1CYP11B2SMN1; SMN2NPC1 | |
| SCHEMBL288637 | 0.65 | F2 (0.40) | CYP19A1CYP11B1CYP11B2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427434-B1 | PROCESS FOR PREPARING BROMO-SUBSTITUTED QUINOLINES | BOEHRINGER INGELHEIM INT (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-8633320-B2 | Process for preparing bromo-substituted quinolines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-21 | — | — | US | disclosed |