SCHEMBL336841

SCHEMBL336841

C=CCOc1nc(O)nc(O)n1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
MAPK1 P28482 2/20 0.47
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
MGMT P16455 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154305 0.95 MAPT (0.47) MAPTMAPK1CDK1CCNB1MGMT
SCHEMBL14410167 0.86 MAPT (0.41) MAPTMAPK1HPGDHSD17B10SMN1; SMN2
SCHEMBL24728020 0.86 MAPT (0.41) MAPTMAPK1
SCHEMBL1195297 0.85 MAPT (0.40) MAPTMAPK1
SCHEMBL23181 0.83 MAPK1 (0.55) MAPTMAPK1CDK1CCNB1MGMT
Hydrogen Sulfide SCHEMBL20395887 0.80 MAPK1 (0.53) MAPTMAPK1CDK1CCNB1MGMT
SCHEMBL24728041 0.79 MAPT (0.39) MAPTMAPK1CDK1CCNB1MGMT
SCHEMBL24141678 0.79 MAPT (0.36) MAPTMAPK1
SCHEMBL11207182 0.79 ALDH1A1 (0.47) MAPTMAPK1HPGDTSHRMEN1
SCHEMBL10798317 0.76 MAPK1 (0.50) MAPTMAPK1CDK1CCNB1MGMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023250039-A1 RECYCLABLE AND MALLEABLE THERMOSETS ENABLED BY ACTIVATING DORMANT DYNAMIC LINKAGES THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) 2023-12-28 WO claimed
CN-114426669-B Modified sepiolite fiber and graft copolymer thereof, tetrapropylfluoride rubber material and sealing rubber ring, and preparation method and application thereof 中国石油化工股份有限公司 2023-08-22 CN claimed
CN-114846066-A Compositions comprising fluoropolymer, benzoyl peroxide, and crosslinker, and related articles and methods 3M创新有限公司 2022-08-02 CN claimed
CN-111040230-B PMI foam with high elongation at break and preparation method thereof 浙江中科恒泰新材料科技有限公司 2022-05-27 CN claimed
CN-114426669-A Modified sepiolite fiber and graft copolymer thereof, tetrapropylene fluoride rubber sizing material, sealing rubber ring, and preparation method and application thereof 中国石油化工股份有限公司 2022-05-03 CN claimed
CN-111655779-B Fluoropolymer compositions comprising nanoparticles functionalized with functional fluorinated silane compounds 3M创新有限公司 2022-04-29 CN claimed
CN-114302913-A Compositions and articles comprising fluoropolymer and branched silsesquioxane polymer 3M创新有限公司 2022-04-08 CN claimed
CN-108472987-B Silica treads cured with peroxide 米其林集团总公司 2021-03-23 CN claimed
CN-111655779-A Fluoropolymer compositions comprising nanoparticles functionalized with functional fluorinated silane compounds 3M创新有限公司 2020-09-11 CN claimed
EP-3069697-B1 METHOD FOR MANUFACTURING A POLYMER SHEET FOR USE AS AN IMMOBILIZATION ELEMENT ORFIT IND (BE) 2019-10-02 EP claimed
US-5578682-A MOLECULAR WEIGHT CONTROL EXXON CHEMICAL PATENTS INC. (US) 1996-11-26 US claimed
EP-0728159-A1 MODIFICATION OF (CO)POLYMERS WITH UNSATURATED PEROXYACIDS Akzo Nobel N.V. (NL) 1996-08-28 EP claimed
WO-1995011938-A1 MODIFICATION OF (CO)POLYMERS WITH UNSATURATED PEROXYACIDS AKZO NOBEL N.V. (NL) 1995-05-04 WO claimed
US-4688605-A Reinforced hose structure THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-08-25 US claimed
US-4329381-A Method for providing corrosion resistance to metal objects HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1982-05-11 US claimed
US-4275175-A BLEND OF ACRYLONITRILE POLYMER AND CITRAL, VINYL STEARATE OR TRIALLYL CYANURATE SCAVENGER MONSANTO COMPANY (US) 1981-06-23 US claimed
US-4258141-A ADDING FIREPROOFING, BLOWING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1981-03-24 US claimed
US-4215085-A BLENDING AN ACRYLONITRILE COPOLYMER AND A SCAVENGER SUCH AS AN UNSATURATED FATTY ALDEHYDE OR ESTER OR CYANURATE MONSANTO COMPANY (US) 1980-07-29 US claimed
US-4196111-A Chemically reducing residual acrylonitrile monomer in nitrile polymers and shaped packaging materials formed therefrom MONSANTO COMPANY (US) 1980-04-01 US claimed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US claimed