Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 4/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394694 | 0.84 | HTR2A (0.34) | HTR2AHTR2C | |
| SCHEMBL16907762 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL5779110 | 0.74 | HTR2A (0.39) | HTR2AHTR2CCHRNB2CHRNA4 | |
| SCHEMBL25333075 | 0.73 | SSTR4 (0.40) | TGFBR1HRH1NNMT | |
| SCHEMBL1937282 | 0.73 | HTR2A (0.39) | TGFBR1HRH1HTR2AHTR2CPNMT | |
| SCHEMBL16906805 | 0.71 | TGFBR1 (0.37) | TGFBR1PARP1PARP2 | |
| SCHEMBL30823972 | 0.71 | KDM4E (0.35) | — | |
| SCHEMBL2002227 | 0.70 | HTR2C (0.39) | HTR2AHTR2CCHRNB2CHRNA4 | |
| SCHEMBL9971963 | 0.70 | MGLL (0.41) | TGFBR1HTR2AHTR2CCHRNB2CHRNA4 | |
| SCHEMBL24731148 | 0.70 | HTR2A (0.36) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049803-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR TREATMENT OF HERPES VIRUSES | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| EP-2872504-B1 | ARYL SULTAM DERIVATIVES AS RORc MODULATORS | HOFFMANN LA ROCHE (CH) | 2016-11-16 | — | — | EP | disclosed |
| WO-2015104356-A1 | ARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015104353-A1 | HETEROARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-07-16 | — | — | WO | disclosed |
| WO-2014009447-A1 | ARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-01-16 | — | — | WO | disclosed |