Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.61 |
| ▸ | GABRE | P78334 | 1/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615370 | 0.82 | PDE4D (0.78) | LMNAHPGDPDE4DGABRA1GABRG2 | |
| Nitrazepam SCHEMBL35202 | 0.79 | PDE4D (1.00) | LMNAHPGDPDE4DGABRA1GABRG2 | |
| Nitrazepam SCHEMBL29408437 | 0.79 | PDE4D (1.00) | LMNAHPGDPDE4DGABRA1GABRG2 | |
| Nitrazepam SCHEMBL9747297 | 0.79 | PDE4D (1.00) | LMNAHPGDPDE4DGABRA1GABRG2 | |
| SCHEMBL13284399 | 0.77 | LMNA (0.78) | LMNAHPGDPDE4DGABRA1GABRG2 | |
| SCHEMBL7721819 | 0.77 | LMNA (0.78) | LMNAHPGDPDE4DGABRA1GABRG2 | |
| SCHEMBL11827239 | 0.77 | PGR (0.67) | LMNAPDE4DGABRA1GABRG2GABRB3 | |
| SCHEMBL3988229 | 0.77 | KMT2A (0.60) | PDE4DGABRA1GABRG2GABRB3GABRA5 | |
| Clonazepam SCHEMBL13747803 | 0.76 | GABRA1 (1.00) | LMNAHPGDPDE4DGABRA1GABRG2 | |
| SCHEMBL7308583 | 0.76 | GABRA1 (0.76) | LMNAHPGDPDE4DGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9347961-B2 | Test kit for the quantitative determination of narcotic drugs | CHIRON AS (NO) | 2016-05-24 | — | — | US | disclosed |
| US-20150204893-A1 | TEST KIT FOR THE QUANTITATIVE DETERMINATION OF NARCOTIC DRUGS | CHIRON AS (NO) | 2015-07-23 | — | — | US | disclosed |
| EP-2687854-A1 | Test kit for the quantitative determination of narcotic drugs | Chiron AS (NO) | 2014-01-22 | — | — | EP | disclosed |