SCHEMBL15436154

SCHEMBL15436154

[CH2]c1cc(C(C)(C)C)c(OC#N)c(C(C)(C)C)c1

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.31
CYP2C19 P33261 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
ALOX15 P16050 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.31
RGS12 O14924 1/20 0.31
NPC1 O15118 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
GLA P06280 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3415521 0.79 SMN1; SMN2 (0.41) CYP2C19ALDH1A1SMN1; SMN2CYP3A4CYP2C9
SCHEMBL11854555 0.77 CA2 (0.43) CYP1A2CYP2C19ALDH1A1SMN1; SMN2TSHR
SCHEMBL11743999 0.76 PTGS2 (0.46) CYP1A2ALDH1A1MAPTALOX15SMN1; SMN2
SCHEMBL3421216 0.72 SMN1; SMN2 (0.38) CYP2C19ALDH1A1MAPTSMN1; SMN2CYP3A4
SCHEMBL15436153 0.71
SCHEMBL1741610 0.71 ALOX15 (0.42) CYP1A2CYP2C19ALDH1A1MAPTALOX15
SCHEMBL3419666 0.71 SMN1; SMN2 (0.37) CYP2C19ALDH1A1ALOX15SMN1; SMN2TP53
SCHEMBL7918964 0.71 HSPA5 (0.50) CYP2C19ALDH1A1SMN1; SMN2CYP3A4CYP2C9
SCHEMBL8151743 0.71 LMNA (0.35) ALOX15LMNATP53CYP3A4HPGD
SCHEMBL3421497 0.70 SMN1; SMN2 (0.36) CYP2C19ALDH1A1SMN1; SMN2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2690120-B1 RESIN COMPOSITION, PREPREG AND RESIN SHEET, AND METAL FOIL-CLAD LAMINATE MITSUBISHI GAS CHEMICAL CO (JP) 2020-06-17 EP disclosed
US-9318402-B2 Resin composition, prepreg and resin sheet and metal foil-clad laminate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-04-19 US disclosed
US-20140073721-A1 RESIN COMPOSITION, PREPREG AND RESIN SHEET AND METAL FOIL-CLAD LAMINATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-03-13 US disclosed
EP-2690120-A1 RESIN COMPOSITION, PREPREG AND RESIN SHEET, AND METAL FOIL-CLAD LAMINATE Mitsubishi Gas Chemical Company, Inc. (JP) 2014-01-29 EP disclosed