Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002747 | 0.84 | PSIP1 (0.31) | PSIP1 | |
| SCHEMBL252924 | 0.79 | CMA1 (0.32) | PSIP1 | |
| SCHEMBL3095947 | 0.77 | PTGDR2 (0.34) | — | |
| SCHEMBL15436284 | 0.66 | CYP2C9 (0.33) | PSIP1 | |
| SCHEMBL15006654 | 0.66 | DRD2 (0.31) | — | |
| SCHEMBL20535193 | 0.66 | TAS1R3 (0.42) | PSIP1 | |
| SCHEMBL2188978 | 0.65 | PSIP1 (0.33) | PSIP1 | |
| SCHEMBL15436289 | 0.61 | — | — | |
| SCHEMBL2187160 | 0.60 | CYP2C9 (0.37) | PSIP1 | |
| SCHEMBL2188973 | 0.59 | PSIP1 (0.38) | PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401269-B1 | INDOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2014-01-29 | — | — | EP | disclosed |