Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 9/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.50 |
| ▸ | PIM1 | P11309 | 4/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.50 |
| ▸ | PRKACA | P17612 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.50 |
| ▸ | CDK9 | P50750 | 3/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.50 |
| ▸ | CDK8 | P49336 | 2/20 | 0.50 |
| ▸ | CLK2 | P49760 | 2/20 | 0.50 |
| ▸ | CDK7 | P50613 | 2/20 | 0.50 |
| ▸ | PRKX | P51817 | 2/20 | 0.50 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.50 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26174487 | 0.87 | RIPK1 (0.57) | CDC7DYRK1APIM1MAP4K4PRKACA | |
| SCHEMBL1748617 | 0.83 | RIPK1 (0.57) | DYRK1APIM1GSK3BCDK5IKBKE | |
| SCHEMBL16719451 | 0.83 | CDC7 (0.45) | CDC7DYRK1APIM1MAP4K4PRKACA | |
| SCHEMBL4780728 | 0.80 | CDK5 (0.55) | CDC7DYRK1AMAP4K4PRKACAGSK3B | |
| SCHEMBL2476987 | 0.80 | CHEK1 (0.54) | PIM1PRKACAPRKD3PRKCQCDK2 | |
| SCHEMBL4780727 | 0.77 | RIPK1 (0.59) | GSK3BCYP19A1CDK2ITKCCNE1 | |
| SCHEMBL5618155 | 0.76 | TGFBR1 (0.71) | CDC7DYRK1APIM1MAP4K4PRKACA | |
| SCHEMBL2274785 | 0.74 | ITK (0.68) | DYRK1ACLK2CYP19A1ITK | |
| SCHEMBL29714858 | 0.74 | ITK (0.68) | DYRK1ACLK2CYP19A1ITK | |
| SCHEMBL25416927 | 0.74 | ITK (0.61) | GSK3BCYP19A1ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |