Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.57 |
| ▸ | CDC7 | O00311 | 6/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 3/20 | 0.54 |
| ▸ | PRKACA | P17612 | 3/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.54 |
| ▸ | CDK9 | P50750 | 3/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.54 |
| ▸ | CDK8 | P49336 | 2/20 | 0.54 |
| ▸ | CLK2 | P49760 | 2/20 | 0.54 |
| ▸ | CDK7 | P50613 | 2/20 | 0.54 |
| ▸ | PRKX | P51817 | 2/20 | 0.54 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.54 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.54 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15436394 | 0.87 | CDC7 (0.50) | CDC7DYRK1AMAP4K4PIM1PRKACA | |
| SCHEMBL1748617 | 0.87 | RIPK1 (0.57) | RIPK1DYRK1APIM1GSK3BCDK5 | |
| SCHEMBL7151357 | 0.79 | RIPK1 (0.57) | RIPK1CDC7 | |
| SCHEMBL5618155 | 0.79 | TGFBR1 (0.71) | CDC7DYRK1AMAP4K4PIM1PRKACA | |
| SCHEMBL27714279 | 0.79 | RIPK1 (0.55) | RIPK1DYRK1ACLK2CDK2CCNE1 | |
| SCHEMBL16719451 | 0.78 | CDC7 (0.45) | CDC7DYRK1AMAP4K4PIM1PRKACA | |
| SCHEMBL1777558 | 0.76 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL16493681 | 0.75 | RIPK1 (0.45) | RIPK1CDC7DYRK1AMAP4K4PIM1 | |
| SCHEMBL1050911 | 0.74 | TGFBR1 (0.60) | CDC7DYRK1AMAP4K4PIM1PRKACA | |
| SCHEMBL15397129 | 0.74 | IKBKE (0.78) | CDC7DYRK1AMAP4K4PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192686-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | RIPK1 273/4885CDC7 688/4885DYRK1A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.