Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195981 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL13195980 | 0.89 | PSMB5 (0.48) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL15436458 | 0.89 | PSMB5 (0.48) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL13195986 | 0.85 | FAAH (0.42) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL15436471 | 0.85 | FAAH (0.42) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL13195577 | 0.83 | CNR2 (0.43) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL15436462 | 0.83 | CNR2 (0.43) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL76313 | 0.76 | CNR2 (0.41) | ALDH1A1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL13195576 | 0.76 | HSD11B1 (0.36) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL15436765 | 0.76 | HSD11B1 (0.36) | ALDH1A1KMT2AMEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687515-A1 | METHOD FOR PRODUCING PYRAZOLECARBOXYLIC ACID DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | HSD11B1, HSD11B2, HSD17B1 | ALDH1A1 115/4885KMT2A 3174/4885MEN1 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.