SCHEMBL146416

SCHEMBL146416

N#CCCCN1CCCC1

nearest known ligand 0.86

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.86
POLB P06746 2/20 0.62
ALDH1A1 P00352 1/20 0.56
PKM P14618 1/20 0.56
HRH3 Q9Y5N1 10/20 0.52
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.40
MAPK1 P28482 1/20 0.40
HRH2 P25021 1/20 0.40
HRH1 P35367 1/20 0.40
GAA P10253 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150332 0.98 MAPT (0.83) MAPTPOLBALDH1A1PKMHRH3
SCHEMBL154378 0.98 MAPT (0.83) MAPTPOLBALDH1A1PKMHRH3
SCHEMBL27895291 0.95
SCHEMBL149979 0.93 MAPT (1.00) MAPTPOLBALDH1A1PKMHRH3
SCHEMBL151720 0.91 MAPT (0.95) MAPTPOLBALDH1A1PKMHRH3
SCHEMBL7224479 0.91 MAPT (0.95) MAPTPOLBALDH1A1PKMHRH3
SCHEMBL151103 0.91 MAPT (0.95) MAPTPOLBALDH1A1PKMHRH3
SCHEMBL9206204 0.91 MAPT (0.95) MAPTPOLBALDH1A1PKMHRH3
SCHEMBL5672438 0.90
SCHEMBL10498707 0.90 ALDH1A1 (0.70) MAPTPOLBALDH1A1PKMHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
EP-1132127-B1 Isolated ultrafine particles TECLE BERHAN (US) 2008-12-24 EP claimed
US-20060049102-A1 Ionic polymer membranes BP CORPORATION NORTH AMERICA INC. 2006-03-09 US claimed
US-6372077-B1 COATING A FIBER WITH A POWDER ENCAPSULANT MATERIAL IN A HIGHLY DISPERSED COLLOIDAL SUSPENSION SUCH THAT THE ENCAPSULATED PARTICLES REMAIN INDEPENDENT AND DISCRETE UPON SEPARATION TECLE BERHAN (US) 2002-04-16 US claimed
EP-0917501-B1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES TECLE BERHAN (US) 2001-09-19 EP claimed
EP-1132127-A2 Method for isolating ultrafine and fine particles and resulting particles Tecle, Berhan (US) 2001-09-12 EP claimed
US-6190731-B1 FORMING A HIGHLY DISPERSED COLLOIDAL SUSPENSION OF PARTICLES, ADDING TO THE SUSPENSION AN ENCAPSULANT MATERIAL TO ENCAPSULATE INDIVIDUAL PARTICLES, AND ISOLATING FROM SAID SUSPENSION INDEPENDENT ENCAPSULATED PARTICLES Tecle, Berhan 2001-02-20 US claimed
US-5922403-A ADDING ENCAPSULANT TO HIGHLY DISPERSED COLLOIDAL SUSPENSION OF SOLID PARTICLES TO ENCAPSULATE INDIVIDUAL PARTICLES; AGGLOMERATING; ISOLATING ENCAPSULATED PARTICLES BY SEPARATION FROM SOLVENT LAYER TECLE, BERHAN 1999-07-13 US claimed
EP-0917501-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES Tecle, Berhan (US) 1999-05-26 EP claimed
WO-1997033713-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES TECLE BERHAN (US) 1997-09-18 WO claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US disclosed
US-20230183177-A1 ENANTIOSELECTIVE CHEMO-ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE AMINO AMIDE COMPOUNDS PHARMAZELL GMBH (DE) 2023-06-15 US disclosed
EP-4139468-A1 ENANTIOSELECTIVE CHEMO-ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE AMINO AMIDE COMPOUNDS Pharmazell GmbH (DE) 2023-03-01 EP disclosed
CN-114678592-B Non-aqueous electrolyte containing cyano cyclic amine compound, lithium ion battery and application thereof 深圳澳睿新能源科技有限公司 2022-09-13 CN disclosed
US-9709907-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-07-18 US disclosed
US-5411995-A Free radically curable formulations employing dithiolate catalysts LOCTITE CORPORATION (US) 1995-05-02 US disclosed
EP-0490769-B1 Aminoalkylketone derivatives, process for their preparation and their therapeutical use LAFON LABOR (FR) 1995-04-19 EP disclosed
US-5217760-A Of a dithiolate and an organic halogen compound and/or tertiary amine coinitiator LOCTITE CORPORATION (US) 1993-06-08 US disclosed
EP-0490769-A1 Aminoalkylketone derivatives, process for their preparation and their therapeutical use LABORATOIRE L. LAFON (FR) 1992-06-17 EP disclosed
EP-0467649-A2 Free radically curable formulations employing dithiolate catalysts LOCTITE CORPORATION (US) 1992-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183177-A1 ENANTIOSELECTIVE CHEMO-ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE AMINO AMIDE COMPOUNDS COASY, NAAA, HNMT MAPT 3930/4885POLB 246/4885ALDH1A1 444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.