SCHEMBL15438286

SCHEMBL15438286

Oc1ccc(C(Cl)(Cl)Cl)cc1C(Cl)(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 4/20 0.38
ALOX15 P16050 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 2/20 0.38
ESR1 P03372 10/20 0.37
CYP2C9 P11712 2/20 0.37
HTT P42858 2/20 0.37
NR1I2 O75469 1/20 0.37
LMNA P02545 1/20 0.37
MIF P14174 1/20 0.37
TYR P14679 1/20 0.37
NFE2L2 Q16236 1/20 0.37
ESR2 Q92731 5/20 0.36
AR P10275 2/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775350 0.76 ESR1 (0.64) TSHRALDH1A1HSD17B10ALOX15TDP1
SCHEMBL10825671 0.76 TSHR (0.62) TSHRALDH1A1HSD17B10ALOX15TDP1
SCHEMBL9308489 0.74 ALDH1A1 (0.63) TSHRALDH1A1HSD17B10ALOX15TDP1
SCHEMBL17696924 0.74 TSHR (0.43) TSHRALDH1A1HSD17B10ALOX15TDP1
SCHEMBL17696928 0.74 CA3 (0.44) TSHRALDH1A1HSD17B10ALOX15TDP1
SCHEMBL11548525 0.73 TSHR (0.65) TSHRTDP1LMNACYP3A4MAPK1
SCHEMBL9297188 0.73 ALOX15 (0.39) TSHRALDH1A1HSD17B10ALOX15TDP1
SCHEMBL6520775 0.73 TSHR (0.41) TSHRALDH1A1HSD17B10ALOX15TDP1
SCHEMBL15438285 0.71 TSHR (0.44) TSHRTDP1CYP3A4MAPK1
SCHEMBL11599924 0.71 TSHR (0.44) TSHRTDP1MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
EP-2698859-B1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND ELECTRICITY-STORAGE DEVICE USING THE SAME UBE INDUSTRIES (JP) 2016-07-27 EP disclosed
US-9384906-B2 Non-aqueous electrolyte solution and electricity-storage device using same UBE INDUSTRIES, LTD. (JP) 2016-07-05 US disclosed
EP-2698859-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND ELECTRICITY-STORAGE DEVICE USING SAME Ube Industries, Ltd. (JP) 2014-02-19 EP disclosed
US-20140030610-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND ELECTRICITY-STORAGE DEVICE USING SAME UBE INDUSTRIES, LTD (JP) 2014-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 TSHR 648/4885ALDH1A1 151/4885HSD17B10 339/4885
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL CBR1, HAO2, CBR3 TSHR 648/4885ALDH1A1 151/4885HSD17B10 339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.