SCHEMBL15438765

SCHEMBL15438765

COP(=O)(CC(=O)Oc1ccc(C(F)(F)F)cc1C(F)(F)F)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
CES2 O00748 2/20 0.41
KDM4E B2RXH2 5/20 0.40
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.40
KMT2A Q03164 1/20 0.40
HPGD P15428 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 2/20 0.38
USP2 O75604 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAPK1 P28482 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
FFAR1 O14842 1/20 0.37
ESRRA P11474 3/20 0.36
HDAC3 O15379 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15438014 0.87 RXRA (0.43) RXRARXRBRXRGCES2KDM4E
SCHEMBL15438935 0.82 PPARG (0.44) RXRARXRBRXRGKDM4EKMT2A
SCHEMBL15438472 0.82 TUBB4A (0.33) HTTKMT2ACYP2C19CYP1A2CYP2C9
SCHEMBL10180243 0.80 RXRA (0.50) RXRARXRBRXRGCES2KDM4E
SCHEMBL15765736 0.80 RXRA (0.52) RXRARXRBRXRGCES2KDM4E
SCHEMBL15438643 0.79 KIF11 (0.46) KDM4EMAPTHTTKMT2AALDH1A1
SCHEMBL15453599 0.79 CES2 (0.49) RXRARXRBRXRGCES2KDM4E
SCHEMBL15438463 0.77 KDM4E (0.48) KDM4EMAPTALDH1A1CYP2C19CYP1A2
SCHEMBL15438129 0.76 RXRA (0.37) RXRARXRBRXRGCES2KDM4E
SCHEMBL15763958 0.76 RXRA (0.46) RXRARXRBRXRGCES2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2698859-B1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND ELECTRICITY-STORAGE DEVICE USING THE SAME UBE INDUSTRIES (JP) 2016-07-27 EP disclosed
US-9384906-B2 Non-aqueous electrolyte solution and electricity-storage device using same UBE INDUSTRIES, LTD. (JP) 2016-07-05 US disclosed
EP-2698859-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND ELECTRICITY-STORAGE DEVICE USING SAME Ube Industries, Ltd. (JP) 2014-02-19 EP disclosed
US-20140030610-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND ELECTRICITY-STORAGE DEVICE USING SAME UBE INDUSTRIES, LTD (JP) 2014-01-30 US disclosed