Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439171 | 1.00 | CES2 (0.40) | CES2CES1RAB9AHPGDNPC1 | |
| SCHEMBL14799499 | 0.88 | ALDH1A1 (0.38) | RAB9AHPGDNPC1KMT2AALDH1A1 | |
| SCHEMBL14799496 | 0.88 | ALDH1A1 (0.38) | RAB9AHPGDNPC1KMT2AALDH1A1 | |
| SCHEMBL15440164 | 0.87 | RAB9A (0.46) | CES2CES1RAB9AHPGDNPC1 | |
| SCHEMBL15440165 | 0.87 | RAB9A (0.46) | CES2CES1RAB9AHPGDNPC1 | |
| SCHEMBL15439440 | 0.81 | NPSR1 (0.36) | CES2CES1RAB9AHPGDNPC1 | |
| SCHEMBL15439442 | 0.81 | NPSR1 (0.36) | CES2CES1RAB9AHPGDNPC1 | |
| SCHEMBL15439680 | 0.81 | CES2 (0.44) | CES2CES1RAB9AHPGDNPC1 | |
| SCHEMBL15439679 | 0.81 | CES2 (0.44) | CES2CES1RAB9AHPGDNPC1 | |
| SCHEMBL15438746 | 0.81 | RAB9A (0.46) | CES2CES1RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |