Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439442 | 1.00 | NPSR1 (0.36) | NPSR1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL14799616 | 0.89 | ALDH1A1 (0.40) | NPSR1ALDH1A1MAPK1GLATSHR | |
| SCHEMBL14799617 | 0.89 | ALDH1A1 (0.40) | NPSR1ALDH1A1MAPK1GLATSHR | |
| SCHEMBL15438746 | 0.85 | RAB9A (0.46) | NPSR1ALDH1A1CES2CES1GLA | |
| SCHEMBL15438743 | 0.85 | RAB9A (0.46) | NPSR1ALDH1A1CES2CES1GLA | |
| SCHEMBL15439828 | 0.83 | CES2 (0.40) | NPSR1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL15439826 | 0.83 | CES2 (0.40) | NPSR1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL15439171 | 0.81 | CES2 (0.40) | NPSR1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL15439172 | 0.81 | CES2 (0.40) | NPSR1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL15439329 | 0.81 | CES2 (0.38) | NPSR1ALDH1A1MAPK1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |