Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEPTOR | Q8TB45 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.33 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439556 | 0.75 | DEPTOR (0.37) | DEPTORPOLBIDO1DNMT1DNMT3L | |
| SCHEMBL15439945 | 0.72 | DEPTOR (0.39) | DEPTORMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15439948 | 0.69 | CFTR (0.34) | MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL15439396 | 0.69 | ALDH1A1 (0.33) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15438847 | 0.69 | CFTR (0.34) | MEN1KMT2AMAPTCYP1A2ALDH1A1 | |
| SCHEMBL15439780 | 0.68 | G6PC1 (0.41) | DEPTORIDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL15439979 | 0.67 | — | — | |
| SCHEMBL15439914 | 0.67 | ALDH1A1 (0.32) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15440099 | 0.67 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15440407 | 0.66 | MAPT (0.34) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |