Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 5/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436292 | 0.85 | NOTUM (0.57) | SLC6A2SLC6A3MAPTHSD17B1HSD17B2 | |
| SCHEMBL22939567 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTHSD17B1HSD17B2SCN9A | |
| SCHEMBL16726594 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTHSD17B14CNR2CNR1 | |
| SCHEMBL22939592 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTSCN9ACNR2LMNA | |
| SCHEMBL14742192 | 0.79 | KMO (0.64) | SLC6A2SLC6A3KMO | |
| SCHEMBL15441619 | 0.79 | KMO (0.63) | HSD17B1HSD17B2KMOSCN9AHSD17B14 | |
| SCHEMBL22939586 | 0.78 | MAPT (0.58) | ALDH1A1MAPTSCN9ALMNA | |
| SCHEMBL22939859 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTSCN9AHSD17B14LMNA | |
| SCHEMBL22939961 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTSCN9ACNR2CNR1 | |
| SCHEMBL22939579 | 0.76 | MAPT (0.59) | ALDH1A1MAPTSCN9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021019051-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2021-02-04 | — | — | WO | disclosed |
| EP-2877452-B1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2017-08-23 | — | — | EP | disclosed |
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| US-9376388-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150191428-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | CORTEVA AGRISCIENCE LLC | 2015-07-09 | — | — | US | disclosed |
| EP-2877453-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | Dow AgroSciences LLC (US) | 2015-06-03 | — | — | EP | disclosed |
| EP-2877452-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | Dow AgroSciences LLC (US) | 2015-06-03 | — | — | EP | disclosed |
| US-9045427-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2014018506-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2014018502-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CLIC4, NPEPPS, CYP4F3 | SLC6A2 654/4885SLC6A3 201/4885ALDH1A1 3201/4885 |
| US-20150191428-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | FLI1, ABL1, FLNA | SLC6A2 3267/4885SLC6A3 2715/4885ALDH1A1 2088/4885 |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | FLI1, ABL1, FLNA | SLC6A2 3267/4885SLC6A3 2715/4885ALDH1A1 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.