Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185246 | 0.86 | TAS1R3 (0.40) | ALDH1A1TAS1R3TAS1R1MEP1BKDM4E | |
| SCHEMBL24985552 | 0.86 | TAS1R3 (0.40) | ALDH1A1TAS1R3TAS1R1MEP1BKDM4E | |
| SCHEMBL2467013 | 0.84 | CNR1 (0.46) | CNR1CNR2KDM4EADORA3ALPL | |
| SCHEMBL3330070 | 0.83 | KDM4E (0.38) | ALDH1A1TAS1R3TAS1R1MEP1BKDM4E | |
| SCHEMBL29489593 | 0.83 | KDM4E (0.38) | ALDH1A1TAS1R3TAS1R1MEP1BKDM4E | |
| SCHEMBL20611020 | 0.81 | MEP1B (0.37) | ALDH1A1TAS1R3TAS1R1MEP1BKDM4E | |
| SCHEMBL14354469 | 0.79 | KDM4E (0.39) | ALDH1A1TAS1R3TAS1R1MEP1BKDM4E | |
| SCHEMBL1918400 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TAS1R3TAS1R1MEP1BTAS1R2 | |
| SCHEMBL28425097 | 0.79 | KDM4E (0.37) | ALDH1A1TAS1R3TAS1R1MEP1BKDM4E | |
| SCHEMBL15440065 | 0.78 | ALDH1A1 (0.44) | CNR1CNR2ALDH1A1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| EP-2877453-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | Dow AgroSciences LLC (US) | 2015-06-03 | — | — | EP | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2014018502-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CLIC4, NPEPPS, CYP4F3 | CNR1 2685/4885CNR2 3237/4885ALDH1A1 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.