Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440555 | 1.00 | CES2 (0.42) | CES2CES1GAACYP2C19RAB9A | |
| SCHEMBL14799745 | 0.87 | ALDH1A1 (0.39) | GAACYP2C19RAB9ANPC1HPGD | |
| SCHEMBL14799744 | 0.87 | ALDH1A1 (0.39) | GAACYP2C19RAB9ANPC1HPGD | |
| SCHEMBL15438509 | 0.86 | RAB9A (0.44) | CES2CES1GAACYP2C19RAB9A | |
| SCHEMBL15438507 | 0.86 | RAB9A (0.44) | CES2CES1GAACYP2C19RAB9A | |
| SCHEMBL15439679 | 0.84 | CES2 (0.44) | CES2CES1GAACYP2C19RAB9A | |
| SCHEMBL15439680 | 0.84 | CES2 (0.44) | CES2CES1GAACYP2C19RAB9A | |
| SCHEMBL15439968 | 0.82 | CES2 (0.48) | CES2CES1GAACYP2C19RAB9A | |
| SCHEMBL15439969 | 0.82 | CES2 (0.48) | CES2CES1GAACYP2C19RAB9A | |
| SCHEMBL15439172 | 0.80 | CES2 (0.40) | CES2CES1GAACYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |