Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495606 | 0.94 | LMNA (0.62) | LMNAHTTHSD17B10MAPTSMN1; SMN2 | |
| 4-Ethoxy-1-Propoxybenzene SCHEMBL2841577 | 0.89 | NQO1 (0.74) | NQO1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2488793 | 0.89 | NQO1 (0.74) | NQO1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2492282 | 0.85 | CYP2D6 (0.59) | HTTSMN1; SMN2L3MBTL1LTA4HKDM4E | |
| SCHEMBL13687719 | 0.84 | LMNA (0.58) | LMNAHTTHSD17B10MAPTL3MBTL1 | |
| SCHEMBL16353273 | 0.84 | KDM4E (0.56) | NQO1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15201648 | 0.83 | NQO1 (0.64) | NQO1LMNAMAPTSMN1; SMN2DHFR | |
| SCHEMBL10027327 | 0.83 | LTA4H (0.70) | NQO1SMN1; SMN2L3MBTL1LTA4HKDM4E | |
| SCHEMBL10027322 | 0.83 | NQO1 (0.64) | NQO1HSD17B10MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7425137 | 0.82 | LMNA (0.53) | LMNAHTTHSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637614-B2 | Reactive liquid modifiers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-01-28 | — | — | US | disclosed |