Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628198 | 0.86 | MMP2 (0.37) | P2RX7DDB1CRBNHSP90AB1MAOA | |
| SCHEMBL13872398 | 0.85 | HSP90AB1 (0.41) | P2RX7DDB1CRBNHSP90AB1MAOA | |
| SCHEMBL28025119 | 0.82 | DGAT1 (0.42) | P2RX7DDB1CRBNDGAT1HSP90AB1 | |
| SCHEMBL21424270 | 0.81 | P2RX7 (0.40) | P2RX7DDB1CRBNDGAT1HSP90AB1 | |
| SCHEMBL20806028 | 0.79 | P2RX7 (0.53) | P2RX7DDB1CRBNHSP90AB1MAOA | |
| SCHEMBL20257915 | 0.79 | HSP90AB1 (0.40) | P2RX7IDO1IDO2DGAT1HSP90AB1 | |
| SCHEMBL19153067 | 0.79 | P2RX7 (0.34) | P2RX7DDB1CRBNDGAT1 | |
| SCHEMBL10067691 | 0.77 | — | — | |
| SCHEMBL24075828 | 0.77 | DGAT1 (0.37) | P2RX7DDB1CRBNDGAT1HSP90AB1 | |
| SCHEMBL28025149 | 0.77 | DGAT1 (0.42) | P2RX7DDB1CRBNDGAT1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2690105-A1 | Mannose derivatives, a process for preparing the same and their uses as a drug | Centre National De La Recherche Scientifique (FR) | 2014-01-29 | — | — | EP | disclosed |