SCHEMBL28025149

SCHEMBL28025149

COCCOCc1cn(C)nn1.F[B-](F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 7/20 0.42
P2RX7 Q99572 2/20 0.33
HSP90AB1 P08238 2/20 0.33
NOTUM Q6P988 2/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025119 0.94 DGAT1 (0.42) DGAT1P2RX7HSP90AB1NOTUMHDAC1
SCHEMBL2628198 0.80 MMP2 (0.37) P2RX7HSP90AB1HDAC1HDAC6HDAC5
SCHEMBL13872398 0.79 HSP90AB1 (0.41) P2RX7HSP90AB1NOTUMHDAC1HDAC6
SCHEMBL21424270 0.79 P2RX7 (0.40) DGAT1P2RX7HSP90AB1DDB1CRBN
SCHEMBL16920302 0.78 P2RX7 (0.36) DGAT1P2RX7HSP90AB1NOTUMHDAC1
SCHEMBL19153067 0.78 P2RX7 (0.34) DGAT1P2RX7DDB1CRBNMMP2
SCHEMBL12049656 0.77
SCHEMBL15445151 0.77 P2RX7 (0.36) DGAT1P2RX7HSP90AB1HDAC1HDAC6
SCHEMBL12033268 0.76 DGAT1 (0.53) DGAT1HSP90AB1
SCHEMBL24075828 0.75 DGAT1 (0.37) DGAT1P2RX7HSP90AB1DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102956917-B Triazole ionic liquid and its preparation method and application Haiyangwang Lighting Technology Co., Ltd. (CN) 2015-08-05 CN disclosed