SCHEMBL15445477

SCHEMBL15445477

CC(O)C(=O)OCCCCCC(=O)OCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PAM P19021 2/20 0.59
MAPT P10636 1/20 0.44
DGKA P23743 1/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
ALDH1A1 P00352 2/20 0.39
LMNA P02545 4/20 0.38
KDM4E B2RXH2 1/20 0.38
DUSP3 P51452 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
DNM1 Q05193 1/20 0.36
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16062674 0.86 DGKA (0.57) MAPTDGKAPRSS1PRSS2PRSS3
SCHEMBL15445476 0.84 ALDH1A1 (0.55) ALDH1A1LMNAMEN1KMT2A
SCHEMBL6550919 0.82 ALDH1A1 (0.52) ALDH1A1LMNAMEN1KMT2A
SCHEMBL12213343 0.81 DGKA (0.47) MAPTDGKAPRSS1PRSS2PRSS3
SCHEMBL4269367 0.81 DGKA (0.67) PAMMAPTDGKAPRSS1PRSS2
SCHEMBL14166378 0.81 DGKA (0.67) PAMMAPTDGKAPRSS1PRSS2
SCHEMBL16062672 0.80 DGKA (0.50) MAPTDGKAPRSS1PRSS2PRSS3
SCHEMBL9791387 0.80 DGKA (0.46) MAPTDGKAPRSS1PRSS2PRSS3
SCHEMBL27697262 0.80 PAM (0.79) PAMMAPTDGKAALDH1A1LMNA
SCHEMBL27714306 0.80 PAM (0.79) PAMMAPTDGKAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9250356-B2 Photochromic polymers VIVIMED LABS EUROPE LTD (GB) 2016-02-02 US disclosed
US-20140027684-A1 PHOTOCHROMIC POLYMERS VIVIMED LABS EUROPE LTD (GB) 2014-01-30 US disclosed