SCHEMBL154455

SCHEMBL154455

CCCCCCCCCCOC(=O)CCCCC(=O)OC(C)CCCC

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.61
LMNA P02545 3/20 0.57
ALDH1A1 P00352 1/20 0.55
MAPT P10636 2/20 0.53
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
NAAA Q02083 1/20 0.51
DNM1 Q05193 1/20 0.51
PRKCA P17252 1/20 0.51
PRKCE Q02156 1/20 0.51
PRKCQ Q04759 1/20 0.51
PRKCD Q05655 1/20 0.51
FAAH O00519 4/20 0.50
CNR1 P21554 1/20 0.50
CNR2 P34972 1/20 0.50
HTR2C P28335 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27544836 1.00 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL22973780 1.00 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL27674246 1.00 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL17046546 0.97 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL17046524 0.97 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL3870936 0.97 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL6136048 0.97 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL3883512 0.97 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL3873893 0.97 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1
SCHEMBL3872055 0.97 DGKA (0.61) DGKALMNAALDH1A1MAPTPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118284399-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-07-02 CN disclosed
CN-118284400-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-07-02 CN disclosed
CN-118265517-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-06-28 CN disclosed
CN-118234468-A Cosmetic product 株式会社资生堂 2024-06-21 CN disclosed
CN-118215462-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-06-18 CN disclosed
CN-118201596-A Cosmetic product 株式会社资生堂 2024-06-14 CN disclosed
CN-118175985-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-06-11 CN disclosed
CN-114641274-B Oil-in-water type composition 株式会社资生堂 2024-06-04 CN disclosed
CN-118076336-A Water-in-oil type emulsified cosmetic 株式会社资生堂 2024-05-24 CN disclosed
CN-118019518-A Water-in-oil type emulsified cosmetic 株式会社资生堂 2024-05-10 CN disclosed
US-20040146472-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-07-29 US disclosed
EP-1430905-A1 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO COMPANY LIMITED (JP) 2004-06-23 EP disclosed
EP-1415639-A1 COMETICS AND MAKEUP METHOD Kanebo, Limited (JP) 2004-05-06 EP disclosed
US-20030158363-A1 Odorless modified silicone compound,cosmetic preparation containing the same, and method of purifying modified silicone compound having branch polymer comprising hydrophilic group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-08-21 US disclosed
US-6607736-B2 Endermic liniment comprising diethoxy ethyl succinate and humectant SHISEIDO COMPANY, LTD. (JP) 2003-08-19 US disclosed
US-20030091603-A1 Skin preparations for external use SHISEIDO COMPANY, LTD. (JP) 2003-05-15 US disclosed
CN-1394138-A Hair growth agent SHISEIDO CO LTD (JP) 2003-01-29 CN disclosed
US-20020131947-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-19 US disclosed
EP-1213316-A2 Polyhydric alcohol-modified silicone and cosmetic material containing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-06-12 EP disclosed
EP-1153602-A1 SKIN PREPARATIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2001-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040146472-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same H1-0, H1-2, H1-3 DGKA 1788/4885LMNA 2208/4885ALDH1A1 733/4885
US-20030091603-A1 Skin preparations for external use CUTA, POLR1C, ACMSD DGKA 2720/4885LMNA 524/4885ALDH1A1 473/4885
US-20020131947-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same H1-0, H1-2, H1-3 DGKA 1788/4885LMNA 2208/4885ALDH1A1 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.