Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615903 | 0.87 | LMNA (0.45) | LMNAP2RX3P2RX4P2RX2 | |
| SCHEMBL7158740 | 0.87 | PRMT6 (0.41) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL2511608 | 0.86 | LMNA (0.42) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL14405904 | 0.86 | LMNA (0.42) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL14853777 | 0.86 | LMNA (0.42) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL22915758 | 0.84 | PRMT6 (0.47) | PRMT6P2RY12LMNAP2RY2P2RY1 | |
| SCHEMBL24649458 | 0.82 | PRMT6 (0.47) | PRMT6P2RY12LMNAP2RY2P2RY1 | |
| SCHEMBL14928997 | 0.81 | PRMT6 (0.43) | PRMT6P2RY12ADORA1BMPR1B | |
| SCHEMBL18561525 | 0.81 | PRMT6 (0.43) | PRMT6P2RY12ADORA1BMPR1B | |
| SCHEMBL13151614 | 0.81 | LMNA (0.45) | PRMT6P2RY12LMNAP2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637475-B1 | Modified 2′ and 3′ nucleoside prodrugs for treating flaviviridae infections | IDENIX PHARMACEUTICALS, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-7608600-B2 | Treating hepatitis C virus infections; antivirals have low toxicity to the host; inhibit Flaviviridae polymerase | IDENIX PHARMACEUTICALS, INC. (US) | 2009-10-27 | — | — | US | disclosed |