Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445650 | 0.87 | PRMT6 (0.44) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL22915758 | 0.80 | PRMT6 (0.47) | PRMT6P2RY12LMNAP2RY2P2RY1 | |
| SCHEMBL7162786 | 0.80 | TAS1R3 (0.47) | — | |
| SCHEMBL24649458 | 0.79 | PRMT6 (0.47) | PRMT6P2RY12LMNAP2RY2P2RY1 | |
| SCHEMBL14853777 | 0.78 | LMNA (0.42) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL14405904 | 0.78 | LMNA (0.42) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL2511608 | 0.78 | LMNA (0.42) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL22983997 | 0.78 | P2RX3 (0.59) | PRMT6P2RY12LMNAP2RX3P2RX4 | |
| SCHEMBL13902897 | 0.76 | P2RY12 (0.64) | P2RY12LMNAP2RX3P2RX4P2RX2 | |
| SCHEMBL14394700 | 0.76 | P2RY12 (0.64) | P2RY12LMNAP2RX3P2RX4P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747389-B1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-RE38090-E1 | Antitumor activity; useful for treatment and prevention of cancers | Matsuda, Akira (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0747389-A1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |