Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22915758 | 0.87 | PRMT6 (0.47) | PRMT6LMNAPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29467365 | 0.83 | PRMT6 (0.45) | PRMT6PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15445650 | 0.82 | PRMT6 (0.44) | PRMT6LMNAP2RY12P2RY2P2RY1 | |
| SCHEMBL29779803 | 0.79 | ADORA1 (0.46) | LMNAP2RY12ADORA2AADORA2B | |
| SCHEMBL22915811 | 0.79 | ADORA1 (0.46) | LMNAP2RY12ADORA2AADORA2B | |
| SCHEMBL5982554 | 0.79 | PRMT6 (0.62) | PRMT6LMNAPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7158740 | 0.79 | PRMT6 (0.41) | PRMT6LMNAP2RY12P2RY2P2RY1 | |
| SCHEMBL31725289 | 0.77 | PRMT6 (0.54) | PRMT6LMNAPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL13151614 | 0.77 | LMNA (0.45) | PRMT6LMNAP2RY12P2RY2P2RY1 | |
| SCHEMBL14388686 | 0.76 | P2RY12 (0.51) | LMNAP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251135-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | BEONE MEDICINES I GMBH (CH) | 2022-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251135-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | STING1, CGAS, MAVS | PRMT6 3041/4885LMNA 2449/4885PRKAB2 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.