Asparagine

Asparagine

SCHEMBL15460

NC(=O)CC(N)C(=O)O.NC(=O)CC(N)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
KMT2A Q03164 1/20 0.56
GRIK1 P39086 8/20 0.54
GRIK2 Q13002 5/20 0.54
GRM1 Q13255 2/20 0.54
GRM2 Q14416 2/20 0.54
SLC7A5 Q01650 1/20 0.52
PTGS1 P23219 1/20 0.50
SLC7A11 Q9UPY5 1/20 0.50
GGT1 P19440 4/20 0.48
SLC1A1 P43005 4/20 0.48
GRIA4 P48058 4/20 0.46
GRIK3 Q13003 4/20 0.46
GRIK5 Q16478 4/20 0.46
SLC1A3 P43003 3/20 0.46
SLC1A2 P43004 3/20 0.46
GRIA2 P42262 3/20 0.46
GRIA1 P42261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL30131205 1.00
Asparagine SCHEMBL8826 1.00
Asparagine SCHEMBL30486685 1.00
Asparagine SCHEMBL150535 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL8827 1.00
Asparagine SCHEMBL288094 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL288093 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL4347082 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL20489207 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL30610983 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 71700 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238363-A1 ORAL PEPTIDE ANTAGONISTS OF MULTIPLE CHEMOKINE RECEPTORS FOR REVERSING LOSS OF SYNAPSES AND DENDRITIC SPINES CREATIVE BIO-PEPTIDES, INC. 2024-07-18 US claimed
CN-118307637-A Peptides, compositions comprising the peptides and use of the peptides in the manufacture of a medicament for the treatment of obesity 3H生物有限公司 2024-07-09 CN claimed
CN-117737026-A GGPPS muteins related to carotenoid content in wheat kernel 河南农业大学 2024-03-22 CN claimed
US-20240084021-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR HIDRADENITIS SUPPURATIVA ANAPTYSBIO, INC. 2024-03-14 US claimed
CN-117630263-A Method for detecting various free amino acids in plasma based on liquid chromatography-tandem mass spectrometry 上海睿质科技有限公司 2024-03-01 CN claimed
WO-2024020083-A2 FUSION PROTEIN INHIBITORS OF KLK5 BIOCRYST PHARMACEUTICALS, INC. (US) 2024-01-25 WO claimed
CN-117230048-A Threonine aldolase mutant with improved stereoselectivity and application thereof 浙江工业大学 2023-12-15 CN claimed
WO-2023176881-A1 COMBINATION OF MULTI-SPECIFIC MOLECULE AND IMMUNE CHECKPOINT INHIBITOR 第一三共株式会社 2023-09-21 WO claimed
US-20230272092-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ICHTHYOSIS ANAPTYSBIO, INC. 2023-08-31 US claimed
CN-116406295-A Anti-interleukin 36 receptor (IL-36R) therapy against ichthyosis 安奈普泰斯生物有限公司 2023-07-07 CN claimed
WO-1987005025-A1 CLONED STREPTOCOCCAL GENES ENCODING PROTEIN G AND THEIR USE TO CONSTRUCT RECOMBINANT MICROORGANISMS TO PRODUCE PROTEIN G GENEX CORPORATION (US) 1987-08-27 WO claimed
WO-1987004728-A1 PEPTIDES FOR THE DIAGNOSIS OF HTLV-III ANTIBODIES, THEIR PREPARATION AND USE CAMBRIDGE BIOSCIENCE CORPORATION (US) 1987-08-13 WO claimed
EP-0230781-A2 Lymphotoxin gene, method for its production, and lymphotoxin DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-08-05 EP claimed
EP-0225128-A1 Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum ELI LILLY AND COMPANY (US) 1987-06-10 EP claimed
EP-0218700-A1 IDENTIFICATION OF AN IgE-BINDING PROTEIN BY MOLECULAR CLONING MEDICAL BIOLOGY INSTITUTE (US) 1987-04-22 EP claimed
EP-0211148-A1 Mature human leukozyte interferons, process for their bacterial production, intermediates therefor and compositions containing them F. HOFFMANN-LA ROCHE AG (CH) 1987-02-25 EP claimed
CN-85101341-A Preparation of high purity protein and its application 1987-01-31 CN claimed
WO-1986006407-A1 IDENTIFICATION OF AN IgE-BINDING PROTEIN BY MOLECULAR CLONING MEDICAL BIOLOGY INSTITUTE (US) 1986-11-06 WO claimed
EP-0118617-A2 Interleukin-2 polypeptides AJINOMOTO CO., INC. (JP) 1984-09-19 EP claimed
WO-1984001150-A1 AVIAN GROWTH HORMONES AMGEN (US) 1984-03-29 WO claimed