Asparagine

Asparagine

SCHEMBL15460

NC(=O)CC(N)C(=O)O.NC(=O)CC(N)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.56
▸ BLM P54132 1/20 0.56
▸ PMP22 Q01453 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ GRIK1 P39086 8/20 0.54
▸ GRIK2 Q13002 5/20 0.54
▸ GRM1 Q13255 2/20 0.54
▸ GRM2 Q14416 2/20 0.54
▸ SLC7A5 Q01650 1/20 0.52
▸ PTGS1 P23219 1/20 0.50
▸ SLC7A11 Q9UPY5 1/20 0.50
▸ GGT1 P19440 4/20 0.48
▸ SLC1A1 P43005 4/20 0.48
▸ GRIA4 P48058 4/20 0.46
▸ GRIK3 Q13003 4/20 0.46
▸ GRIK5 Q16478 4/20 0.46
▸ SLC1A3 P43003 3/20 0.46
▸ SLC1A2 P43004 3/20 0.46
▸ GRIA2 P42262 3/20 0.46
▸ GRIA1 P42261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL30131205 1.00 — —
Asparagine SCHEMBL8827 1.00 — —
Asparagine SCHEMBL30486685 1.00 — —
Asparagine SCHEMBL288094 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL288093 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL4347082 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL8826 1.00 — —
Asparagine SCHEMBL150535 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL20489207 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL30610983 1.00 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 71700 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238363-A1 ORAL PEPTIDE ANTAGONISTS OF MULTIPLE CHEMOKINE RECEPTORS FOR REVERSING LOSS OF SYNAPSES AND DENDRITIC SPINES CREATIVE BIO-PEPTIDES, INC. 2024-07-18 — — US claimed
CN-118307637-A Peptides, compositions comprising the peptides and use of the peptides in the manufacture of a medicament for the treatment of obesity 3H生物有限公司 2024-07-09 — — CN claimed
CN-117737026-A GGPPS muteins related to carotenoid content in wheat kernel 河南农业大学 2024-03-22 — — CN claimed
US-20240084021-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR HIDRADENITIS SUPPURATIVA ANAPTYSBIO, INC. 2024-03-14 — — US claimed
CN-117630263-A Method for detecting various free amino acids in plasma based on liquid chromatography-tandem mass spectrometry 上海睿质科技有限公司 2024-03-01 — — CN claimed
WO-2024020083-A2 FUSION PROTEIN INHIBITORS OF KLK5 BIOCRYST PHARMACEUTICALS, INC. (US) 2024-01-25 — — WO claimed
CN-117230048-A Threonine aldolase mutant with improved stereoselectivity and application thereof 浙江工业大学 2023-12-15 — — CN claimed
WO-2023176881-A1 COMBINATION OF MULTI-SPECIFIC MOLECULE AND IMMUNE CHECKPOINT INHIBITOR 第一三共株式会社 2023-09-21 — — WO claimed
US-20230272092-A1 ANTI-INTERLEUKIN 36 RECEPTOR (IL-36R) THERAPY FOR ICHTHYOSIS ANAPTYSBIO, INC. 2023-08-31 — — US claimed
CN-116406295-A Anti-interleukin 36 receptor (IL-36R) therapy against ichthyosis 安奈普泰斯生物有限公司 2023-07-07 — — CN claimed
WO-1987005025-A1 CLONED STREPTOCOCCAL GENES ENCODING PROTEIN G AND THEIR USE TO CONSTRUCT RECOMBINANT MICROORGANISMS TO PRODUCE PROTEIN G GENEX CORPORATION (US) 1987-08-27 — — WO claimed
WO-1987004728-A1 PEPTIDES FOR THE DIAGNOSIS OF HTLV-III ANTIBODIES, THEIR PREPARATION AND USE CAMBRIDGE BIOSCIENCE CORPORATION (US) 1987-08-13 — — WO claimed
EP-0230781-A2 Lymphotoxin gene, method for its production, and lymphotoxin DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-08-05 — — EP claimed
EP-0225128-A1 Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum ELI LILLY AND COMPANY (US) 1987-06-10 — — EP claimed
EP-0218700-A1 IDENTIFICATION OF AN IgE-BINDING PROTEIN BY MOLECULAR CLONING MEDICAL BIOLOGY INSTITUTE (US) 1987-04-22 — — EP claimed
EP-0211148-A1 Mature human leukozyte interferons, process for their bacterial production, intermediates therefor and compositions containing them F. HOFFMANN-LA ROCHE AG (CH) 1987-02-25 — — EP claimed
CN-85101341-A Preparation of high purity protein and its application — 1987-01-31 — — CN claimed
WO-1986006407-A1 IDENTIFICATION OF AN IgE-BINDING PROTEIN BY MOLECULAR CLONING MEDICAL BIOLOGY INSTITUTE (US) 1986-11-06 — — WO claimed
EP-0118617-A2 Interleukin-2 polypeptides AJINOMOTO CO., INC. (JP) 1984-09-19 — — EP claimed
WO-1984001150-A1 AVIAN GROWTH HORMONES AMGEN (US) 1984-03-29 — — WO claimed
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