Asparagine

Asparagine

SCHEMBL20489207

NC(=O)C[C@@H](N)C(=O)O.NC(=O)C[C@@H](N)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
KMT2A Q03164 1/20 0.56
GRIK1 P39086 8/20 0.54
GRIK2 Q13002 5/20 0.54
GRM1 Q13255 2/20 0.54
GRM2 Q14416 2/20 0.54
SLC7A5 Q01650 1/20 0.52
PTGS1 P23219 1/20 0.50
SLC7A11 Q9UPY5 1/20 0.50
GGT1 P19440 4/20 0.48
SLC1A1 P43005 4/20 0.48
GRIA4 P48058 4/20 0.46
GRIK3 Q13003 4/20 0.46
GRIK5 Q16478 4/20 0.46
SLC1A3 P43003 3/20 0.46
SLC1A2 P43004 3/20 0.46
GRIA2 P42262 3/20 0.46
GRIA1 P42261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL30131205 1.00
Asparagine SCHEMBL8826 1.00
Asparagine SCHEMBL30486685 1.00
Asparagine SCHEMBL150535 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL8827 1.00
Asparagine SCHEMBL288094 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL288093 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL4347082 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL15460 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL30610983 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018160158-A1 SYNERGISTIC COMPOSITION FOR MAINTENANCE OF HEALTHY BALANCE OF MICROFLORA KIMBERLY-CLARK WORLDWIDE, INC. (US) 2018-09-07 WO disclosed