Asparagine

Asparagine

SCHEMBL4347082

NC(=O)CC(N)C(=O)O.NC(=O)CC(N)C(=O)O.NC(=O)CC(N)C(=O)O.NC(=O)CC(N)C(=O)O.NC(=O)CC(N)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
KMT2A Q03164 1/20 0.56
GRIK1 P39086 8/20 0.54
GRIK2 Q13002 5/20 0.54
GRM1 Q13255 2/20 0.54
GRM2 Q14416 2/20 0.54
SLC7A5 Q01650 1/20 0.52
PTGS1 P23219 1/20 0.50
SLC7A11 Q9UPY5 1/20 0.50
GGT1 P19440 4/20 0.48
SLC1A1 P43005 4/20 0.48
GRIA4 P48058 4/20 0.46
GRIK3 Q13003 4/20 0.46
GRIK5 Q16478 4/20 0.46
SLC1A3 P43003 3/20 0.46
SLC1A2 P43004 3/20 0.46
GRIA2 P42262 3/20 0.46
GRIA1 P42261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL30131205 1.00
Asparagine SCHEMBL8826 1.00
Asparagine SCHEMBL30486685 1.00
Asparagine SCHEMBL150535 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL8827 1.00
Asparagine SCHEMBL288094 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL288093 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL15460 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL20489207 1.00 ALOX15 (0.56) ALOX15BLMPMP22KMT2AGRIK1
Asparagine SCHEMBL30610983 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542845-A1 PLASMODIUM FALCIPARUM ANTIGEN FOR ELICITING PROTECTIVE ANTIBODIES FOR USE IN VACCINES. PASTEUR INSTITUT (FR) 1993-05-26 EP claimed
CN-112166188-B Method for producing ethanol using engineered yeast 嘉吉有限公司 2024-07-02 CN disclosed
CN-111471719-B Efficient non-meiotic allele introgression 重组股份有限公司 2024-06-18 CN disclosed
CN-110628729-B Baculovirus and composition for detecting and preventing porcine epidemic diarrhea virus infection 周美吟 2024-05-28 CN disclosed
CN-113826013-B Polypeptide magnetic nanoparticle, preparation method and application thereof 北京中科纳泰生物科技有限公司 2024-05-24 CN disclosed
CN-117858945-A Modification of HECT E3 ubiquitin ligase gene for improved yield traits 成对植物服务股份有限公司 2024-04-09 CN disclosed
CN-111983220-B Polypeptide magnetic nanoparticle, preparation method and application thereof 北京中科纳泰生物科技有限公司 2024-03-19 CN disclosed
CN-110582567-B Genetically modified trehalase-expressing yeasts and fermentation methods using such genetically modified yeasts 嘉吉公司 2024-03-08 CN disclosed
CN-111979162-B Recombinant bacillus calmette-guerin strain, preparation method and application thereof 上海市公共卫生临床中心 2024-02-13 CN disclosed
CN-112996803-B Phosphoric acid transposition device BIOC3公司 2024-02-13 CN disclosed
US-5342755-A Complexing with streptokinase and lactate dehydrogenase GEORGETOWN UNIVERSITY (US) 1994-08-30 US disclosed
WO-1994017187-A1 CLONING AND EXPRESSION OF PLASMODIUM FALCIPARUM TRANSMISSION-BLOCKING TARGET ANTIGEN, Pfs230 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-08-04 WO disclosed
EP-0542845-A1 PLASMODIUM FALCIPARUM ANTIGEN FOR ELICITING PROTECTIVE ANTIBODIES FOR USE IN VACCINES. PASTEUR INSTITUT (FR) 1993-05-26 EP disclosed
WO-1993009235-A2 UBIQUITIN-SPECIFIC PROTEASES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-05-13 WO disclosed
WO-1993002704-A1 MIXTURE OF PEPTIDE CONSTITUENTS HAVING VACCINATING PROPERTIES AGAINST PALUDISM PARTICULARLY DUE TO PLASMODIUM FALCIPARUM INSTITUT PASTEUR (FR) 1993-02-18 WO disclosed
WO-1993003057-A1 POLYPEPTIDES CAPABLE OF IN VIVO INDUCTION OF ANTIBODIES THEMSELVES CAPABLE OF INHIBITING THE INVASION OF RED BLOOD CORPUSCLES BY MEROZOITES OF P.FALCIPARUM, RELATED PRODUCTS AND THEIR USE IN PRODUCING VACCINE COMPOSITIONS INSTITUT PASTEUR (FR) 1993-02-18 WO disclosed
WO-1992002549-A1 PLASMODIUM FALCIPARUM ANTIGEN FOR ELICITING PROTECTIVE ANTIBODIES FOR USE IN VACCINES INSTITUT PASTEUR (FR) 1992-02-20 WO disclosed
WO-1991008756-A1 NOVEL MALARIAL SPOROZOITE PEPTIDE ANTIGENS BIOMEDICAL RESEARCH INSTITUTE (US) 1991-06-27 WO disclosed
WO-1988008165-A1 COMPUTER BASED METHOD FOR PROTEIN ENGINEERING GENEX CORPORATION (US) 1988-10-20 WO disclosed
WO-1988008164-A1 COMPUTER DESIGNED STABILIZED PROTEINS AND METHOD FOR PRODUCING SAME GENEX CORPORATION (US) 1988-10-20 WO disclosed