Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602763 | 0.79 | S100B (0.50) | S100BITGB3ITGAVTSHRPNMT | |
| SCHEMBL1547384 | 0.79 | — | — | |
| SCHEMBL4130846 | 0.78 | POLB (0.52) | S100BITGB3ITGAVTSHRCYP1A2 | |
| SCHEMBL11687193 | 0.77 | S100B (0.48) | S100BITGB3ITGAVTSHRPNMT | |
| SCHEMBL11112707 | 0.75 | S100B (0.47) | S100BITGB3ITGAVTSHRPNMT | |
| SCHEMBL12463823 | 0.75 | S100B (0.47) | S100BITGB3ITGAVTSHRPNMT | |
| SCHEMBL3304879 | 0.75 | S100B (0.47) | S100BITGB3ITGAVTSHRPNMT | |
| SCHEMBL12441830 | 0.75 | S100B (0.47) | S100BITGB3ITGAVTSHRPNMT | |
| SCHEMBL8165573 | 0.75 | PNMT (0.45) | S100BITGB3ITGAVTSHRPNMT | |
| Ammonia Solution, Strong SCHEMBL11452982 | 0.73 | S100B (0.46) | S100BITGB3ITGAVTSHRPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311816-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |
| EP-2311817-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |
| EP-2308858-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-20100137372-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2139874-A2 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008126665-A2 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137372-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | CYP4X1, PRDX5, PRDX1 | S100B 4771/4885ITGB3 3447/4885ITGAV 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.