SCHEMBL3304879

SCHEMBL3304879

C=Nc1cccc(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGAV P06756 1/20 0.47
TSHR P16473 3/20 0.42
PNMT P11086 2/20 0.39
GALR3 O60755 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 1/20 0.38
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
LMNA P02545 2/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
DRD2 P14416 2/20 0.35
DRD3 P35462 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11452982 0.98 S100B (0.46) S100BITGB3ITGAVTSHRPNMT
SCHEMBL3728747 0.79
SCHEMBL8602763 0.79 S100B (0.50) S100BITGB3ITGAVTSHRPNMT
SCHEMBL8417246 0.78 S100B (0.46) S100BITGB3ITGAVTSHRPNMT
SCHEMBL11687193 0.77 S100B (0.48) S100BITGB3ITGAVTSHRPNMT
SCHEMBL12441830 0.75 S100B (0.47) S100BITGB3ITGAVTSHRPNMT
SCHEMBL12463823 0.75 S100B (0.47) S100BITGB3ITGAVTSHRPNMT
SCHEMBL11112707 0.75 S100B (0.47) S100BITGB3ITGAVTSHRPNMT
SCHEMBL1546431 0.75 S100B (0.47) S100BITGB3ITGAVTSHRPNMT
SCHEMBL14701089 0.73 S100B (0.46) S100BITGB3ITGAVTSHRPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4130139-A Flexible hose construction and method of making same DAYCO CORPORATION (US) 1978-12-19 US claimed
US-20260077300-A1 Gas Separation Membrane, Method For Manufacturing Gas Separation Membrane, And Gas Separation Apparatus SEIKO EPSON CORP (JP) 2026-03-19 US disclosed
US-12577410-B2 Rheology control agents for water-based resins and water-based paint compositions KUSUMOTO CHEMICALS, LTD. (JP) 2026-03-17 US disclosed
EP-4644499-A1 VISCOSITY ADJUSTMENT AGENT, ADHESION IMPROVEMENT AGENT, AND NON-WATER-BASED PAINT COMPOSITION Kusumoto Chemicals, Ltd. (JP) 2025-11-05 EP disclosed
US-12441884-B2 Rheology control agent and curable composition using the same KUSUMOTO CHEMICALS, LTD. (JP) 2025-10-14 US disclosed
EP-3873975-B1 COATED INFILL AND ARTIFICIAL TURF WITH THE COATED INFILL DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-28 EP disclosed
EP-4552718-A1 ANTIFOAMING AGENT COMPOSITION, AQUEOUS COATING COMPOSITION AND ARTICLE Kusumoto Chemicals, Ltd. (JP) 2025-05-14 EP disclosed
US-12281245-B2 Moisture curable adhesive compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-22 US disclosed
EP-3906269-B1 MOISTURE CURABLE ADHESIVE COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-16 EP disclosed
CN-114174366-B Polyurethane foam with improved combustion properties 陶氏环球技术有限责任公司 2025-03-14 CN disclosed
US-4143003-A AS POLYMERIZATION CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
EP-0000761-A1 Process for the preparation of polyurethane foams BAYER AG (DE) 1979-02-21 EP disclosed
EP-0000389-A1 Process for the preparation of polyurethane resins BAYER AG (DE) 1979-01-24 EP disclosed
US-4130139-A Flexible hose construction and method of making same DAYCO CORPORATION (US) 1978-12-19 US disclosed
US-4119613-A Process for the production of polyisocyanate-polyaddition products using a multi-phase reaction flow tube BAYER AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4090547-A Pneumatic tire for vehicles LIM-HOLDING S.A. (LU) 1978-05-23 US disclosed
US-4034789-A Pneumatic tire having a removable tread ring THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-07-12 US disclosed
US-3970733-A Method of making an encapsulated chain THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-07-20 US disclosed
US-3956451-A Method of making an ornamental styled wheel MOTOR WHEEL CORPORATION (US) 1976-05-11 US disclosed
US-3956448-A Method of centrifugally casting a tire THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577410-B2 Rheology control agents for water-based resins and water-based paint compositions RER1, WDR82, CA1 S100B 3632/4885ITGB3 2917/4885ITGAV 2364/4885
US-20260077300-A1 Gas Separation Membrane, Method For Manufacturing Gas Separation Membrane, And Gas Separation Apparatus TBXAS1, TGOLN2, TCP1 S100B 2033/4885ITGB3 213/4885ITGAV 951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.