Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15466655 | 0.92 | EPHX2 (0.34) | P2RX7DDR1TRPV1EPHX2NR1H4 | |
| SCHEMBL15466458 | 0.91 | P2RX7 (0.35) | P2RX7DDR1MAPTKHKEPHX2 | |
| SCHEMBL794953 | 0.90 | ALDH1A1 (0.35) | MAPTEPHX2ALDH1A1 | |
| SCHEMBL15466959 | 0.89 | KCNH2 (0.41) | P2RX7EPHX2KCNH2MCHR1 | |
| SCHEMBL794663 | 0.84 | P2RX7 (0.33) | P2RX7DDR1TRPV1EPHX2NR1H4 | |
| SCHEMBL794782 | 0.84 | TRPV1 (0.37) | P2RX7DDR1TRPV1EPHX2KCNH2 | |
| SCHEMBL15467152 | 0.84 | ATF1 (0.40) | TRPV1EPHX2NR1H4 | |
| SCHEMBL798214 | 0.83 | EPHX2 (0.35) | P2RX7DDR1EPHX2KCNH2NR1H4 | |
| SCHEMBL15465826 | 0.83 | TRPV1 (0.37) | P2RX7TRPV1EPHX2DRD2NR1H4 | |
| SCHEMBL795219 | 0.81 | KDM4E (0.34) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | P2RX7 750/4885DDR1 4208/4885TRPV1 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.