Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287484 | 0.74 | BCHE (0.47) | — | |
| SCHEMBL791815 | 0.74 | NPC1 (0.40) | SLC6A4SLC6A3PDE10A | |
| SCHEMBL17842392 | 0.73 | CHRM1 (0.54) | CHRM2CHRM1CHRM3 | |
| SCHEMBL5158440 | 0.73 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL32667680 | 0.73 | SLC2A1 (0.44) | HTR2CHTR2BHTR2AHTR7CHRM3 | |
| SCHEMBL17842187 | 0.73 | CHRM1 (0.36) | SLC6A2SLC6A4CHRM2CHRM1CHRM3 | |
| SCHEMBL28087406 | 0.72 | KCNK3 (0.37) | — | |
| SCHEMBL4144918 | 0.72 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL4144913 | 0.72 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL4471193 | 0.72 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188002-A | A kind of substituted piperidine base ethyl n-butyrate. quaternary ammonium salt and preparation method thereof | 重庆华邦制药有限公司 | 2016-12-07 | — | — | CN | claimed |
| US-20210206719-A1 | AMINO ALCOHOL-BORON-BINOL COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVE BY USING SAME | MOLECULES & MATERIALS CO., LTD. (KR) | 2021-07-08 | — | — | US | disclosed |
| CN-113072486-A | Amino alcohol-boron-binaphthol complex and preparation method of optically active amino alcohol derivative using same | 分子与物质株式会社 | 2021-07-06 | — | — | CN | disclosed |
| CN-109957585-A | A kind of method that biocatalysis technique prepares (S)-(4- chlorphenyl) -2- pyridinemethanol | 尚科生物医药（上海）有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-106188002-A | A kind of substituted piperidine base ethyl n-butyrate. quaternary ammonium salt and preparation method thereof | 重庆华邦制药有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-106146462-A | The synthetic method of 4-[(S)-(4-chlorphenyl)-2-pyridinyl methoxy]-piperidino isopropyl isobutyrate | 重庆华邦胜凯制药有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-105669652-A | Improved preparation method of bepotastine besilate | 石家庄格瑞药业有限公司 | 2016-06-15 | — | — | CN | disclosed |
| US-20140046068-A1 | METHOD OF SYNTHESIZING BEPOTASTINE OR BENZENESULFONIC ACID SALT THEREOF AND INTERMEDIATES USED THEREIN | EVERLIGHT USA, INC. (US) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206719-A1 | AMINO ALCOHOL-BORON-BINOL COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVE BY USING SAME | BCAT1, BCAT2, HBS1L | SLC6A2 1133/4885SLC6A4 1828/4885SLC6A3 1120/4885 |
| US-20140046068-A1 | METHOD OF SYNTHESIZING BEPOTASTINE OR BENZENESULFONIC ACID SALT THEREOF AND INTERMEDIATES USED THEREIN | CYP7A1, HRH3, HRH2 | SLC6A2 1342/4885SLC6A4 1680/4885SLC6A3 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.