Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.34 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.34 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.34 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832706 | 0.84 | TBXA2R (0.34) | KCNK3KCNK9GPR119FAAHTBXA2R | |
| SCHEMBL1287484 | 0.75 | BCHE (0.47) | TBXA2RHRH3 | |
| SCHEMBL15467458 | 0.72 | SLC6A2 (0.41) | — | |
| SCHEMBL28111368 | 0.70 | TBXA2R (0.35) | GPR119FAAHTBXA2R | |
| SCHEMBL8727056 | 0.70 | BCHE (0.44) | TBXA2R | |
| SCHEMBL10486946 | 0.67 | LMNA (0.46) | — | |
| SCHEMBL28081660 | 0.66 | CYP2C19 (0.37) | TBXA2R | |
| SCHEMBL9034346 | 0.66 | BCHE (0.39) | CACNA1G | |
| SCHEMBL23293089 | 0.66 | GPR119 (0.52) | GPR119 | |
| SCHEMBL29487581 | 0.66 | GPR119 (0.52) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146462-A | The synthetic method of 4-[(S)-(4-chlorphenyl)-2-pyridinyl methoxy]-piperidino isopropyl isobutyrate | 重庆华邦胜凯制药有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-106146462-A | The synthetic method of 4-[(S)-(4-chlorphenyl)-2-pyridinyl methoxy]-piperidino isopropyl isobutyrate | 重庆华邦胜凯制药有限公司 | 2016-11-23 | — | — | CN | disclosed |