Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468305 | 0.92 | CA1 (0.39) | MAPK1ALDH1A1HPGDGFERLMNA | |
| SCHEMBL418973 | 0.90 | PIK3CD (0.34) | ALDH1A1POLBCHRM2CHRM4CHRM5 | |
| SCHEMBL14585063 | 0.90 | PIK3CD (0.34) | ALDH1A1POLBCHRM2CHRM4CHRM5 | |
| SCHEMBL15468307 | 0.84 | ALDH1A1 (0.38) | MAPK1ALDH1A1HPGDGFERACHE | |
| SCHEMBL17577746 | 0.77 | PKM (0.31) | ALDH1A1POLBPIK3CD | |
| SCHEMBL14170548 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGDGFERACHE | |
| SCHEMBL14170536 | 0.76 | ALDH1A1 (0.35) | MAPK1ALDH1A1HPGDGFER | |
| SCHEMBL15468310 | 0.75 | CA1 (0.32) | CA1CA2CA4 | |
| SCHEMBL10079285 | 0.74 | MAPK1 (0.36) | MAPK1ALDH1A1LMNATP53NPSR1 | |
| SCHEMBL14170527 | 0.74 | ALDH1A1 (0.34) | MAPK1ALDH1A1HPGDGFERLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648094-B2 | IAP BIR domain binding compounds | PHARMASCIENCE, INC. (CA) | 2014-02-11 | — | — | US | disclosed |