Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468310 | 0.88 | CA1 (0.32) | CA1CA2CA4 | |
| SCHEMBL15468302 | 0.84 | MAPK1 (0.36) | ALDH1A1HPGDGFERMAPK1ACHE | |
| SCHEMBL15468305 | 0.80 | CA1 (0.39) | ALDH1A1HPGDGFERMAPK1LMNA | |
| SCHEMBL17577746 | 0.77 | PKM (0.31) | ALDH1A1POLB | |
| SCHEMBL14585063 | 0.72 | PIK3CD (0.34) | ALDH1A1POLBCA1CA2CA4 | |
| SCHEMBL418973 | 0.72 | PIK3CD (0.34) | ALDH1A1POLBCA1CA2CA4 | |
| SCHEMBL14170536 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HPGDGFERMAPK1 | |
| SCHEMBL14170527 | 0.71 | ALDH1A1 (0.34) | ALDH1A1HPGDGFERMAPK1LMNA | |
| SCHEMBL13722579 | 0.69 | NOS1 (0.36) | ALDH1A1MAPK1LMNAPOLBGAA | |
| SCHEMBL7713426 | 0.69 | XIAP (0.36) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648094-B2 | IAP BIR domain binding compounds | PHARMASCIENCE, INC. (CA) | 2014-02-11 | — | — | US | disclosed |