Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468307 | 0.88 | ALDH1A1 (0.38) | CA1CA2CA4 | |
| SCHEMBL14585063 | 0.84 | PIK3CD (0.34) | CA1CA2CA4KMT2A | |
| SCHEMBL17577746 | 0.84 | PKM (0.31) | — | |
| SCHEMBL418973 | 0.84 | PIK3CD (0.34) | CA1CA2CA4KMT2A | |
| SCHEMBL15468305 | 0.79 | CA1 (0.39) | CA1CA2CA4KMT2A | |
| SCHEMBL17775468 | 0.79 | CYP3A4 (0.36) | — | |
| SCHEMBL15468302 | 0.75 | MAPK1 (0.36) | CA1CA2CA4 | |
| SCHEMBL6012053 | 0.74 | XIAP (0.30) | — | |
| SCHEMBL12053484 | 0.72 | CYP3A4 (0.38) | — | |
| SCHEMBL14169190 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648094-B2 | IAP BIR domain binding compounds | PHARMASCIENCE, INC. (CA) | 2014-02-11 | — | — | US | disclosed |