Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386821 | 0.89 | ALDH1A1 (0.40) | ALDH1A1CES2CES1GPR52KDM4E | |
| SCHEMBL8834551 | 0.83 | LMNA (0.47) | ALDH1A1CES1GPR52KDM4ELMNA | |
| SCHEMBL18413039 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CES2CES1KDM4ELMNA | |
| SCHEMBL25930723 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CES2CES1GPR52KDM4E | |
| SCHEMBL9366290 | 0.79 | GPR52 (0.63) | ALDH1A1CES2CES1GPR52KDM4E | |
| SCHEMBL9366295 | 0.79 | GPR52 (0.63) | ALDH1A1CES2CES1GPR52KDM4E | |
| SCHEMBL22402333 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CES2CES1GPR52KDM4E | |
| SCHEMBL16127998 | 0.76 | ALDH1A1 (0.43) | ALDH1A1CES2CES1GPR52KDM4E | |
| SCHEMBL2540583 | 0.75 | CES2 (0.44) | ALDH1A1CES2CES1GPR52KDM4E | |
| SCHEMBL24327301 | 0.75 | ALDH1A1 (0.46) | ALDH1A1CES2CES1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828179-A1 | CYANOPYRROLIDINES AS DUB MODULATORS | Mission Therapeutics Limited (GB) | 2021-06-02 | — | — | EP | disclosed |
| EP-2696385-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE | Konica Minolta, Inc. (JP) | 2014-02-12 | — | — | EP | disclosed |