Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531113 | 1.00 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL18644348 | 0.90 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL21660257 | 0.90 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL28012265 | 0.90 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL9191203 | 0.90 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL24311830 | 0.90 | TDP1 (0.49) | CTSKCTSS | |
| SCHEMBL14279380 | 0.90 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL3735437 | 0.90 | CA1 (0.49) | CTSKCTSS | |
| SCHEMBL8089276 | 0.89 | CTSK (0.55) | CTSKCTSS | |
| SCHEMBL2074989 | 0.89 | CTSK (0.55) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541050-B2 | Pyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2023-01-03 | — | — | US | disclosed |
| US-20210228713-A1 | TLR7 PEPTIDE CONJUGATES | Apros Therapeutics, Inc. | 2021-07-29 | — | — | US | disclosed |
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |
| US-20210023082-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2021-01-28 | — | — | US | disclosed |
| US-10780089-B2 | Pyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2020-09-22 | — | — | US | disclosed |
| US-10647684-B2 | 2-aminopyrimidine derivatives for the treatment of viral infections | Janssen Sciences Ireland Unlimited Company (IE) | 2020-05-12 | — | — | US | disclosed |
| US-20200061059-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2020-02-27 | — | — | US | disclosed |
| US-10420767-B2 | Pyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2019-09-24 | — | — | US | disclosed |
| US-10272085-B2 | Pyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2019-04-30 | — | — | US | disclosed |
| US-10259793-B2 | 2-aminopyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2019-04-16 | — | — | US | disclosed |
| US-9598378-B2 | 2-aminopyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2017-03-21 | — | — | US | disclosed |
| US-9598378-B2 | 2-aminopyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2017-03-21 | — | — | US | disclosed |
| US-9422250-B2 | Pyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2016-08-23 | — | — | US | disclosed |
| US-9422250-B2 | Pyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2016-08-23 | — | — | US | disclosed |
| US-8916575-B2 | Quinazoline derivatives for the treatment of viral infections and further diseases | JANSSEN R&D IRELAND (IE) | 2014-12-23 | — | — | US | disclosed |
| US-8916575-B2 | Quinazoline derivatives for the treatment of viral infections and further diseases | JANSSEN R&D IRELAND (IE) | 2014-12-23 | — | — | US | disclosed |
| US-20140073642-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | JANSSEN R&D IRELAND (IE) | 2014-03-13 | — | — | US | disclosed |
| US-20140073642-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | JANSSEN R&D IRELAND (IE) | 2014-03-13 | — | — | US | disclosed |
| US-20140045849-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2014-02-13 | — | — | US | disclosed |
| US-20140045849-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073642-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | TLR3, TLR5, TLR4 | CTSK 1039/4885CTSS 1528/4885 |
| US-10780089-B2 | Pyrimidine derivatives for the treatment of viral infections | TYMP, UMPS, HPRT1 | CTSK 3614/4885CTSS 3574/4885 |
| US-10647684-B2 | 2-aminopyrimidine derivatives for the treatment of viral infections | DPYD, EIF2AK2, TYMP | CTSK 3549/4885CTSS 3182/4885 |
| US-20200061059-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | TYMP, UMPS, HPRT1 | CTSK 3614/4885CTSS 3574/4885 |
| US-20210228713-A1 | TLR7 PEPTIDE CONJUGATES | TLR7, TLR9, TLR8 | CTSK 2220/4885CTSS 2997/4885 |
| US-10420767-B2 | Pyrimidine derivatives for the treatment of viral infections | TYMP, UMPS, HPRT1 | CTSK 3614/4885CTSS 3574/4885 |
| US-20140045849-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | TYMP, UMPS, HPRT1 | CTSK 3614/4885CTSS 3574/4885 |
| US-10272085-B2 | Pyrimidine derivatives for the treatment of viral infections | TYMP, UMPS, HPRT1 | CTSK 3614/4885CTSS 3574/4885 |
| US-10259793-B2 | 2-aminopyrimidine derivatives for the treatment of viral infections | DPYD, EIF2AK2, TYMP | CTSK 3549/4885CTSS 3182/4885 |
| US-11541050-B2 | Pyrimidine derivatives for the treatment of viral infections | TYMP, UMPS, HPRT1 | CTSK 3614/4885CTSS 3574/4885 |
| US-20210023082-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | TYMP, UMPS, HPRT1 | CTSK 3614/4885CTSS 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.