SCHEMBL15470646

SCHEMBL15470646

CCC(C)c1cccc2c(C(=O)OC(C)(C)C3CC=C(C)CC3)cccc12

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
CYP3A4 P08684 2/20 0.37
ALOX15 P16050 2/20 0.37
PTPN1 P18031 1/20 0.33
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
CHRNA7 P36544 1/20 0.32
STAT3 P40763 1/20 0.32
CES2 O00748 1/20 0.32
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14825876 0.81 HSP90AA1 (0.35) LMNATSHR
SCHEMBL15470634 0.79 LMNA (0.39) LMNACYP3A4ALOX15PTPN1MEN1
SCHEMBL15470644 0.77 LMNA (0.41) LMNACYP3A4ALOX15PTPN1MEN1
SCHEMBL6304031 0.77 LMNA (0.43) LMNACYP3A4ALOX15PTPN1MEN1
SCHEMBL15470538 0.76 LMNA (0.40) LMNACYP3A4ALOX15PTPN1MEN1
SCHEMBL3503694 0.74 LMNA (0.44) LMNACYP3A4ALOX15PTPN1MEN1
SCHEMBL29655401 0.74 LMNA (0.44) LMNACYP3A4ALOX15PTPN1MEN1
SCHEMBL29318958 0.72 TSHR (0.39) ALDH1A1TSHR
SCHEMBL5604543 0.71 CES2 (0.51) LMNACYP3A4ALOX15PTPN1MEN1
SCHEMBL3504597 0.70 LMNA (0.50) LMNACYP3A4ALOX15PTPN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9075308-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-07 US disclosed
US-20140045122-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed