SCHEMBL1547527

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL472320	0.91	PDE3B (0.39)	PDE3BPDE3ARECQLPKM
	SCHEMBL472735	0.88	PDE3B (0.38)	PDE3BPDE3ARECQLMAPTKDM4E
	SCHEMBL3068888	0.88	CA1 (0.31)	PDE3BPDE3ARECQLPKMCA1
	SCHEMBL1609340	0.88	CYP3A4 (0.36)	PDE3BPDE3ARECQLMAPTESR2
	SCHEMBL1610490	0.88	NISCH (0.37)	RECQLMAPTKDM4EPKMCA1
	SCHEMBL1611047	0.86	RECQL (0.36)	PDE3BPDE3ARECQLTDP1PKM
	SCHEMBL3063198	0.86	RECQL (0.32)	RECQLKDM4EPKM
	SCHEMBL472668	0.86	CA1 (0.32)	PDE3BPDE3ARECQLPKMCA1
	SCHEMBL1612058	0.86	CA1 (0.33)	RECQLMAPTKDM4EPKMCA1
	SCHEMBL740175	0.86	TDP1 (0.36)	PDE3BPDE3ARECQLMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.