Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13101604 | 0.90 | — | — | |
| SCHEMBL3121012 | 0.89 | CYP11B2 (0.39) | RECQLPKMCYP11B1CYP11B2 | |
| SCHEMBL3114036 | 0.88 | CYP11B2 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL3123674 | 0.87 | RECQL (0.32) | RECQLPKMKDM4ECYP11B1CYP11B2 | |
| SCHEMBL1468094 | 0.87 | KDM4E (0.34) | RECQLPKMKDM4ECYP11B1CYP11B2 | |
| SCHEMBL3116717 | 0.87 | RECQL (0.32) | RECQLPKMKDM4ECYP11B1CYP11B2 | |
| SCHEMBL30016435 | 0.87 | BACE1 (0.35) | RECQLPKMKDM4ECYP11B1CYP11B2 | |
| SCHEMBL718167 | 0.87 | BACE1 (0.35) | RECQLPKMKDM4ECYP11B1CYP11B2 | |
| SCHEMBL1547527 | 0.86 | PDE3B (0.38) | RECQLPKMKDM4E | |
| SCHEMBL472320 | 0.86 | PDE3B (0.39) | RECQLPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230913-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-18 | — | — | EP | disclosed |
| EP-2230913-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-18 | — | — | EP | disclosed |
| US-8410145-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410145-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100273832-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273832-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| EP-2230913-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009077197-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009077197-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273832-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | RECQL 602/4885PKM 3973/4885KDM4E 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.