Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 4/20 | 0.52 |
| ▸ | PGK2 | P07205 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29023595 | 1.00 | PGK1 (0.52) | PGK1PGK2TSHRALDH1A1CYP3A4 | |
| Phosphoric Acid SCHEMBL31047197 | 0.97 | PGK1 (0.50) | PGK1PGK2TSHRALDH1A1CYP3A4 | |
| Phosphoric Acid SCHEMBL28506645 | 0.88 | ALDH1A1 (0.72) | PGK1PGK2TSHRALDH1A1CYP3A4 | |
| Phosphoric Acid SCHEMBL27559349 | 0.86 | PGK1 (0.43) | PGK1PGK2TSHRALDH1A1CYP3A4 | |
| M-Xylene SCHEMBL867616 | 0.82 | ACHE (0.67) | TSHRALDH1A1MAPK1TDP1LMNA | |
| M-Xylene SCHEMBL31175845 | 0.82 | ACHE (0.67) | TSHRALDH1A1MAPK1TDP1LMNA | |
| M-Xylene SCHEMBL379656 | 0.82 | ACHE (0.67) | TSHRALDH1A1MAPK1TDP1LMNA | |
| SCHEMBL3353801 | 0.82 | PGK1 (0.44) | PGK1PGK2TSHRALDH1A1CYP3A4 | |
| M-Xylene SCHEMBL31175847 | 0.82 | ACHE (0.67) | TSHRALDH1A1MAPK1TDP1LMNA | |
| M-Xylene SCHEMBL29023600 | 0.82 | ACHE (0.67) | TSHRALDH1A1MAPK1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228491-A1 | INJECTION MOLDING MEANS | GINAR TECHNOLOGY CO., LTD (TW) | 2014-08-14 | — | — | US | claimed |
| US-20140050815-A1 | INJECTION MOLDING MEANS | GINAR TECHNOLOGY CO., LTD (TW) | 2014-02-20 | — | — | US | claimed |
| CN-106795719-A | Antiflaming floor material and its manufacture method | 乐金华奥斯株式会社 | 2017-05-31 | — | — | CN | disclosed |
| US-20140228491-A1 | INJECTION MOLDING MEANS | GINAR TECHNOLOGY CO., LTD (TW) | 2014-08-14 | — | — | US | disclosed |
| US-20140050815-A1 | INJECTION MOLDING MEANS | GINAR TECHNOLOGY CO., LTD (TW) | 2014-02-20 | — | — | US | disclosed |