Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490510 | 0.89 | KCNMA1 (0.50) | KCNMA1MEN1KMT2AF10ALDH1A1 | |
| SCHEMBL1490404 | 0.82 | MAPT (0.43) | KCNMA1MEN1KMT2AF10ALDH1A1 | |
| SCHEMBL1490251 | 0.79 | KCNMA1 (0.46) | KCNMA1LMNAMAPTHTTNPSR1 | |
| SCHEMBL12756909 | 0.74 | GAA (0.45) | KCNMA1MEN1KMT2AF10LMNA | |
| SCHEMBL1490539 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL1490228 | 0.71 | TAS1R3 (0.45) | KCNMA1MEN1KMT2AF10ALDH1A1 | |
| SCHEMBL15479129 | 0.71 | PPARG (0.60) | KCNMA1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11515491 | 0.69 | ALDH1A1 (0.82) | KCNMA1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14363387 | 0.69 | KCNMA1 (0.75) | KCNMA1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL1490580 | 0.69 | KCNMA1 (0.47) | KCNMA1LMNAMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051711-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051711-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | KCNMA1 91/4885MEN1 2958/4885KMT2A 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.